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Down-Regulation of Nicotinamide N-methyltransferase Induces Apoptosis in Human Breast Cancer Cells via the Mitochondria-Mediated Pathway

Nicotinamide N-methyltransferase (NNMT) has been found involved in cell proliferation of several malignancies. However, the functional role of NNMT in breast cancer has not been elucidated. In the present study, we showed that NNMT was selectively expressed in some breast cancer cell lines, down-reg...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Wang, Yanzhong, Li, Guiling, Yu, Haitao, Xie, Xinyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928407/
https://www.ncbi.nlm.nih.gov/pubmed/24558488
http://dx.doi.org/10.1371/journal.pone.0089202