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Induction of Atrial Fibrillation by Neutrophils Critically Depends on CD11b/CD18 Integrins

BACKGROUND: Recent observational clinical and ex-vivo studies suggest that inflammation and in particular leukocyte activation predisposes to atrial fibrillation (AF). However, whether local binding and extravasation of leukocytes into atrial myocardium is an essential prerequisite for the initiatio...

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Detalles Bibliográficos
Autores principales: Friedrichs, Kai, Adam, Matti, Remane, Lisa, Mollenhauer, Martin, Rudolph, Volker, Rudolph, Tanja K., Andrié, René P., Stöckigt, Florian, Schrickel, Jan W., Ravekes, Thorben, Deuschl, Florian, Nickenig, Georg, Willems, Stephan, Baldus, Stephan, Klinke, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928425/
https://www.ncbi.nlm.nih.gov/pubmed/24558493
http://dx.doi.org/10.1371/journal.pone.0089307