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Desmoglein 2 Depletion Leads to Increased Migration and Upregulation of the Chemoattractant Secretoneurin in Melanoma Cells

During development and progression of malignant melanoma, an important role has been attributed to alterations of cell-cell adhesions, in particular, to a “cadherin switch” from E- to N-cadherin. We have previously shown that a subtype of melanoma cells express the desmosomal cadherin desmoglein 2 a...

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Detalles Bibliográficos
Autores principales: Peitsch, Wiebke K., Doerflinger, Yvette, Fischer-Colbrie, Reiner, Huck, Volker, Bauer, Alexander T., Utikal, Jochen, Goerdt, Sergij, Schneider, Stefan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928442/
https://www.ncbi.nlm.nih.gov/pubmed/24558503
http://dx.doi.org/10.1371/journal.pone.0089491