Self-microemulsifying drug-delivery system for improved oral bioavailability of 20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol: preparation and evaluation

The objective of this study was to develop a self-microemulsifying drug delivery system (SMEDDS) to enhance the oral bioavailability of the poorly water-soluble compound 20(S)-25-methoxydammarane-3β;12β;20-triol (25-OCH(3)-PPD). Optimized SMEDDS formulations for 25-OCH(3)-PPD contained Cremophor® EL...

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Detalles Bibliográficos
Autores principales: Cai, Shuang, Shi, Cai-Hong, Zhang, Xiangrong, Tang, Xiaojiao, Suo, Hao, Yang, Li, Zhao, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928458/
https://www.ncbi.nlm.nih.gov/pubmed/24611008
http://dx.doi.org/10.2147/IJN.S56894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928458/
https://www.ncbi.nlm.nih.gov/pubmed/24611008
http://dx.doi.org/10.2147/IJN.S56894

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