Midazolam induces apoptosis in MA-10 mouse Leydig tumor cells through caspase activation and the involvement of MAPK signaling pathway

PURPOSE: The present study aims to investigate how midazolam, a sedative drug for clinical use with cytotoxicity on neuronal and peripheral tissues, induced apoptosis in MA-10 mouse Leydig tumor cells. METHODS: The apoptotic effect and underlying mechanism of midazolam to MA-10 cells were investigat...

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Detalles Bibliográficos
Autores principales: So, Edmund Cheung, Lin, Yu-Xuan, Tseng, Chi Hao, Pan, Bo-Syong, Cheng, Ka-Shun, Wong, Kar-Lok, Hao, Lyh-Jyh, Wang, Yang-Kao, Huang, Bu-Miin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928462/
https://www.ncbi.nlm.nih.gov/pubmed/24611016
http://dx.doi.org/10.2147/OTT.S56084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928462/
https://www.ncbi.nlm.nih.gov/pubmed/24611016
http://dx.doi.org/10.2147/OTT.S56084

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