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Sequence-based Gaussian network model for protein dynamics

Motivation: Gaussian network model (GNM) is widely adopted to analyze and understand protein dynamics, function and conformational changes. The existing GNM-based approaches require atomic coordinates of the corresponding protein and cannot be used when only the sequence is known. Results: We report...

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Detalles Bibliográficos
Autores principales: Zhang, Hua, Kurgan, Lukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928524/
https://www.ncbi.nlm.nih.gov/pubmed/24336646
http://dx.doi.org/10.1093/bioinformatics/btt716