HIV-1 evades innate immune recognition through specific co-factor recruitment

HIV-1 is able to replicate in primary human macrophages without stimulating innate immunity despite reverse transcription of genomic RNA into double stranded DNA, an activity that might be expected to trigger innate pattern recognition receptors (PRRs). We hypothesized that, if correctly orchestrate...

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Detalles Bibliográficos
Autores principales: Rasaiyaah, Jane, Tan, Choon Ping, Fletcher, Adam J., Price, Amanda J., Blondeau, Caroline, Hilditch, Laura, Jacques, David A, Selwood, David L, James, Leo C, Noursadeghi, Mahdad, Towers, Greg J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928559/
https://www.ncbi.nlm.nih.gov/pubmed/24196705
http://dx.doi.org/10.1038/nature12769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928559/
https://www.ncbi.nlm.nih.gov/pubmed/24196705
http://dx.doi.org/10.1038/nature12769

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