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HIV-1 evades innate immune recognition through specific co-factor recruitment
HIV-1 is able to replicate in primary human macrophages without stimulating innate immunity despite reverse transcription of genomic RNA into double stranded DNA, an activity that might be expected to trigger innate pattern recognition receptors (PRRs). We hypothesized that, if correctly orchestrate...
Autores principales: | Rasaiyaah, Jane, Tan, Choon Ping, Fletcher, Adam J., Price, Amanda J., Blondeau, Caroline, Hilditch, Laura, Jacques, David A, Selwood, David L, James, Leo C, Noursadeghi, Mahdad, Towers, Greg J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928559/ https://www.ncbi.nlm.nih.gov/pubmed/24196705 http://dx.doi.org/10.1038/nature12769 |
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