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Harnessing the Heterogeneity of T Cell Differentiation Fate to Fine-Tune Generation of Effector and Memory T Cells

Recent studies show that naïve T cells bearing identical T cell receptors experience heterogeneous differentiation and clonal expansion processes. The factors controlling this outcome are not well characterized, and their contributions to immune cell dynamics are similarly poorly understood. In this...

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Detalles Bibliográficos
Autores principales: Gong, Chang, Linderman, Jennifer J., Kirschner, Denise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928592/
https://www.ncbi.nlm.nih.gov/pubmed/24600448
http://dx.doi.org/10.3389/fimmu.2014.00057