Single-base resolution of mouse offspring brain methylome reveals epigenome modifications caused by gestational folic acid

BACKGROUND: Epigenetic modifications, such as cytosine methylation in CpG-rich regions, regulate multiple functions in mammalian development. Maternal nutrients affecting one-carbon metabolism during gestation can exert long-term effects on the health of the progeny. Using C57BL/6 J mice, we investi...

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Detalles Bibliográficos
Autores principales: Barua, Subit, Kuizon, Salomon, Chadman, Kathryn K, Flory, Michael J, Brown, W Ted, Junaid, Mohammed A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928622/
https://www.ncbi.nlm.nih.gov/pubmed/24484737
http://dx.doi.org/10.1186/1756-8935-7-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928622/
https://www.ncbi.nlm.nih.gov/pubmed/24484737
http://dx.doi.org/10.1186/1756-8935-7-3

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