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Dietary supplementation of arachidonic acid increases arachidonic acid and lipoxin A(4) contents in colon, but does not affect severity or prostaglandin E(2) content in murine colitis model

BACKGROUND: Arachidonic acid (ARA) is an essential fatty acid and a major constituent of biomembranes. It is converted into various lipid mediators, such as prostaglandin E(2) (PGE(2)) and lipoxin A(4) (LXA(4)). The effects of dietary ARA on colon maintenance are unclear because PGE(2) has both muco...

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Detalles Bibliográficos
Autores principales: Tateishi, Norifumi, Kakutani, Saki, Kawashima, Hiroshi, Shibata, Hiroshi, Morita, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928921/
https://www.ncbi.nlm.nih.gov/pubmed/24507383
http://dx.doi.org/10.1186/1476-511X-13-30