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Targeting Survivin in Cancer: Novel Drug Development Approaches
Survivin is a well-established target in experimental cancer therapy. The molecule is over-expressed in most human tumors, but hardly detectable in normal tissues. Multiple functions in different subcellular compartments have been assigned. It participates in the control of cell division, apoptosis,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929033/ https://www.ncbi.nlm.nih.gov/pubmed/23955284 http://dx.doi.org/10.1007/s40259-013-0058-x |