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Targeting Survivin in Cancer: Novel Drug Development Approaches

Survivin is a well-established target in experimental cancer therapy. The molecule is over-expressed in most human tumors, but hardly detectable in normal tissues. Multiple functions in different subcellular compartments have been assigned. It participates in the control of cell division, apoptosis,...

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Detalles Bibliográficos
Autores principales: Groner, Bernd, Weiss, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929033/
https://www.ncbi.nlm.nih.gov/pubmed/23955284
http://dx.doi.org/10.1007/s40259-013-0058-x