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High-resolution mapping of transcription factor binding sites on native chromatin

Sequence-specific DNA-binding proteins including transcription factors (TFs) are key determinants of gene regulation and chromatin architecture. Formaldehyde cross-linking and sonication followed by Chromatin ImmunoPrecipitation (X-ChIP) is widely used for profiling of TF binding, but is limited by...

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Detalles Bibliográficos
Autores principales: Kasinathan, Sivakanthan, Orsi, Guillermo A., Zentner, Gabriel E., Ahmad, Kami, Henikoff, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929178/
https://www.ncbi.nlm.nih.gov/pubmed/24336359
http://dx.doi.org/10.1038/nmeth.2766