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Pharmacodynamics of TRPV1 Agonists in a Bioassay Using Human PC-3 Cells

Purpose. TRPV1 is a multimodal channel mainly expressed in sensory neurons. We aimed to explore the pharmacodynamics of the TRPV1 agonists, capsaicin, natural capsaicinoids, and piperine in an in vitro bioassay using human PC-3 cells and to examine desensitization and the effect of the specific anta...

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Detalles Bibliográficos
Autores principales: Alvarez-Berdugo, Daniel, Jiménez, Marcel, Clavé, Pere, Rofes, Laia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929291/
https://www.ncbi.nlm.nih.gov/pubmed/24688365
http://dx.doi.org/10.1155/2014/184526