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Effects of CYP2D6 and UGT2B7 polymorphisms on pharmacokinetics of tamoxifen in Thai breast cancer patients

PURPOSE: The objective of this study was to evaluate the impact of CYP2D6 and UGT2B7 polymorphisms on tamoxifen (TAM) pharmacokinetics in Thai breast cancer patients. METHODS: Thai female breast cancer patients treated with TAM were included in the study. Patients were genotyped for CYP2D6 and UGT2B...

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Detalles Bibliográficos
Autores principales: Areepium, N, Panomvana, D, Rungwanonchai, P, Sathaporn, S, Voravud, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929327/
https://www.ncbi.nlm.nih.gov/pubmed/24648760
http://dx.doi.org/10.2147/BCTT.S47172