Benzimidazoisoquinolines: A New Class of Rapidly Metabolized Aryl Hydrocarbon Receptor (AhR) Ligands that Induce AhR-Dependent Tregs and Prevent Murine Graft-Versus-Host Disease

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that plays multiple roles in regulation of immune and inflammatory responses. The ability of certain AhR ligands to induce regulatory T cells (Tregs) has generated interest in developing AhR ligands for therapeutic treatm...

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Detalles Bibliográficos
Autores principales: Punj, Sumit, Kopparapu, Prasad, Jang, Hyo Sang, Phillips, Jessica L., Pennington, Jamie, Rohlman, Diana, O’Donnell, Edmond, Iversen, Patrick L., Kolluri, Siva Kumar, Kerkvliet, Nancy I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929365/
https://www.ncbi.nlm.nih.gov/pubmed/24586378
http://dx.doi.org/10.1371/journal.pone.0088726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929365/
https://www.ncbi.nlm.nih.gov/pubmed/24586378
http://dx.doi.org/10.1371/journal.pone.0088726

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