Deficient Phosphorylation of Stat1 in Leukocytes Identifies Neutralizing Antibodies in Multiple Sclerosis Patients Treated with Interferon-Beta

BACKGROUND: Anti interferon-beta (IFN-β) neutralizing antibodies (NAb) affect efficacy of treatment of multiple sclerosis patients, but exactly when the detrimental effects of NAbs offset therapeutic efficacy is debated. Quantification of intracellular pathway-specific phosphorylation by phospho-spe...

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Detalles Bibliográficos
Autores principales: Gavasso, Sonia, Mosleth, Ellen Faergestad, Marøy, Tove, Jørgensen, Katarina, Nakkestad, Hanne-Linda, Gjertsen, Bjørn-Tore, Myhr, Kjell-Morten, Vedeler, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929401/
https://www.ncbi.nlm.nih.gov/pubmed/24586361
http://dx.doi.org/10.1371/journal.pone.0088632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929401/
https://www.ncbi.nlm.nih.gov/pubmed/24586361
http://dx.doi.org/10.1371/journal.pone.0088632

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