Cargando…

Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential

The development of efficient strategies for generating fully human monoclonal antibodies with unique functional properties that are exploitable for tailored therapeutic interventions remains a major challenge in the antibody technology field. Here, we present a methodology for recovering such antibo...

Descripción completa

Detalles Bibliográficos
Autores principales: Diebolder, Philipp, Keller, Armin, Haase, Stephanie, Schlegelmilch, Anne, Kiefer, Jonathan D, Karimi, Tamana, Weber, Tobias, Moldenhauer, Gerhard, Kehm, Roland, Eis-Hübinger, Anna M, Jäger, Dirk, Federspil, Philippe A, Herold-Mende, Christel, Dyckhoff, Gerhard, Kontermann, Roland E, Arndt, Michaela AE, Krauss, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929437/
https://www.ncbi.nlm.nih.gov/pubmed/24256717
http://dx.doi.org/10.4161/mabs.27236