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Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential
The development of efficient strategies for generating fully human monoclonal antibodies with unique functional properties that are exploitable for tailored therapeutic interventions remains a major challenge in the antibody technology field. Here, we present a methodology for recovering such antibo...
Autores principales: | Diebolder, Philipp, Keller, Armin, Haase, Stephanie, Schlegelmilch, Anne, Kiefer, Jonathan D, Karimi, Tamana, Weber, Tobias, Moldenhauer, Gerhard, Kehm, Roland, Eis-Hübinger, Anna M, Jäger, Dirk, Federspil, Philippe A, Herold-Mende, Christel, Dyckhoff, Gerhard, Kontermann, Roland E, Arndt, Michaela AE, Krauss, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929437/ https://www.ncbi.nlm.nih.gov/pubmed/24256717 http://dx.doi.org/10.4161/mabs.27236 |
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