The influence of antibody fragment format on phage display based affinity maturation of IgG

Today, most approved therapeutic antibodies are provided as immunoglobulin G (IgG), whereas small recombinant antibody formats are required for in vitro antibody generation and engineering during drug development. Particularly, single chain (sc) antibody fragments like scFv or scFab are well suited...

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Detalles Bibliográficos
Autores principales: Steinwand, Miriam, Droste, Patrick, Frenzel, Andrè, Hust, Michael, Dübel, Stefan, Schirrmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929444/
https://www.ncbi.nlm.nih.gov/pubmed/24262918
http://dx.doi.org/10.4161/mabs.27227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929444/
https://www.ncbi.nlm.nih.gov/pubmed/24262918
http://dx.doi.org/10.4161/mabs.27227

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