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Methods for site-specific drug conjugation to antibodies
Antibody drug conjugates (ADCs) are an emerging class of targeted therapeutics with the potential to improve therapeutic index over traditional chemotherapy. Drugs and linkers have been the current focus of ADC development, in addition to antibody and target selection. Recently, however, the importa...
Autores principales: | Behrens, Christopher R, Liu, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929454/ https://www.ncbi.nlm.nih.gov/pubmed/24135651 http://dx.doi.org/10.4161/mabs.26632 |
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