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Eucommia ulmoides Cortex, Geniposide and Aucubin Regulate Lipotoxicity through the Inhibition of Lysosomal BAX

In this study we examined the inhibition of hepatic dyslipidemia by Eucommia ulmoides extract (EUE). Using a screening assay for BAX inhibition we determined that EUE regulates BAX-induced cell death. Among various cell death stimuli tested EUE regulated palmitate-induced cell death, which involves...

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Detalles Bibliográficos
Autores principales: Lee, Geum-Hwa, Lee, Mi-Rin, Lee, Hwa-Young, Kim, Seung Hyun, Kim, Hye-Kyung, Kim, Hyung-Ryong, Chae, Han-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929538/
https://www.ncbi.nlm.nih.gov/pubmed/24586300
http://dx.doi.org/10.1371/journal.pone.0088017