Tristetraprolin Mediates Anti-Inflammatory Effect of Carbon Monoxide against DSS-Induced Colitis

Endogenous carbon monoxide (CO) exerts anti-inflammatory effects. Tristetraprolin (TTP) is known to destabilize pro-inflammatory transcripts. Here we found that exogenous CO enhanced the decay of TNF-α mRNA and suppressed TNF-α expression in LPS-activated macrophages from wild-type (WT) mice. Howeve...

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Detalles Bibliográficos
Autores principales: Joe, Yeonsoo, Uddin, Md. Jamal, Zheng, Min, Kim, Hyo Jeong, Chen, Yingqing, Yoon, Nal Ae, Cho, Gyeong Jae, Park, Jeong Woo, Chung, Hun Taeg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929600/
https://www.ncbi.nlm.nih.gov/pubmed/24586391
http://dx.doi.org/10.1371/journal.pone.0088776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929600/
https://www.ncbi.nlm.nih.gov/pubmed/24586391
http://dx.doi.org/10.1371/journal.pone.0088776

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