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Tristetraprolin Mediates Anti-Inflammatory Effect of Carbon Monoxide against DSS-Induced Colitis
Endogenous carbon monoxide (CO) exerts anti-inflammatory effects. Tristetraprolin (TTP) is known to destabilize pro-inflammatory transcripts. Here we found that exogenous CO enhanced the decay of TNF-α mRNA and suppressed TNF-α expression in LPS-activated macrophages from wild-type (WT) mice. Howeve...
Autores principales: | Joe, Yeonsoo, Uddin, Md. Jamal, Zheng, Min, Kim, Hyo Jeong, Chen, Yingqing, Yoon, Nal Ae, Cho, Gyeong Jae, Park, Jeong Woo, Chung, Hun Taeg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929600/ https://www.ncbi.nlm.nih.gov/pubmed/24586391 http://dx.doi.org/10.1371/journal.pone.0088776 |
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