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Leptin Acts Independently of Food Intake to Modulate Gut Microbial Composition in Male Mice

Shifts in the composition of gut bacterial populations can alter host metabolism and may contribute to the pathogenesis of metabolic disorders, including obesity. Mice deficient in leptin action are obese with altered microbiota and increased susceptibility to certain intestinal pathogens. Because a...

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Detalles Bibliográficos
Autores principales: Rajala, Michael W., Patterson, Christa M., Opp, Judith S., Foltin, Susan K., Young, Vincent B., Myers, Martin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929727/
https://www.ncbi.nlm.nih.gov/pubmed/24424041
http://dx.doi.org/10.1210/en.2013-1085