The Teratogenic Effects of Prenatal Ethanol Exposure Are Exacerbated by Sonic Hedgehog or Gli2 Haploinsufficiency in the Mouse

Disruption of the Hedgehog signaling pathway has been implicated as an important molecular mechanism in the pathogenesis of fetal alcohol syndrome. In severe cases, the abnormalities of the face and brain that result from prenatal ethanol exposure fall within the spectrum of holoprosencephaly. Singl...

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Detalles Bibliográficos
Autores principales: Kietzman, Henry W., Everson, Joshua L., Sulik, Kathleen K., Lipinski, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929747/
https://www.ncbi.nlm.nih.gov/pubmed/24586787
http://dx.doi.org/10.1371/journal.pone.0089448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929747/
https://www.ncbi.nlm.nih.gov/pubmed/24586787
http://dx.doi.org/10.1371/journal.pone.0089448

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