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CD44s signals the acquisition of the mesenchymal phenotype required for anchorage-independent cell survival in hepatocellular carcinoma

BACKGROUND: Circulating tumour cells (CTCs) have an important role in metastatic processes, but details of their basic characteristics remain elusive. We hypothesised that CD44-expressing CTCs show a mesenchymal phenotype and high potential for survival in hepatocellular carcinoma (HCC). METHODS: Ci...

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Detalles Bibliográficos
Autores principales: Okabe, H, Ishimoto, T, Mima, K, Nakagawa, S, Hayashi, H, Kuroki, H, Imai, K, Nitta, H, Saito, S, Hashimoto, D, Chikamoto, A, Ishiko, T, Watanabe, M, Nagano, O, Beppu, T, Saya, H, Baba, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929866/
https://www.ncbi.nlm.nih.gov/pubmed/24300972
http://dx.doi.org/10.1038/bjc.2013.759