FGFR2 amplification has prognostic significance in gastric cancer: results from a large international multicentre study

BACKGROUND: In preclinical gastric cancer (GC) models, FGFR2 amplification was associated with increased tumour cell proliferation and survival, and drugs targeting this pathway are now in clinical trials. METHODS: FGFR2 FISH was performed on 961 GCs from the United Kingdom, China and Korea, and the...

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Detalles Bibliográficos
Autores principales: Su, X, Zhan, P, Gavine, P R, Morgan, S, Womack, C, Ni, X, Shen, D, Bang, Y-J, Im, S-A, Ho Kim, W, Jung, E-J, Grabsch, H I, Kilgour, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929881/
https://www.ncbi.nlm.nih.gov/pubmed/24457912
http://dx.doi.org/10.1038/bjc.2013.802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929881/
https://www.ncbi.nlm.nih.gov/pubmed/24457912
http://dx.doi.org/10.1038/bjc.2013.802

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