Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancer

BACKGROUND: Jumonji domain-containing protein 2B (JMJD2B), directly targeted by hypoxia-inducible factor 1α, maintains the histone methylation balance important for the transcriptional activation of many oncogenes. Jumonji domain-containing protein 2B has been implicated in colorectal cancer (CRC) p...

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Detalles Bibliográficos
Autores principales: Chen, L, Fu, L, Kong, X, Xu, J, Wang, Z, Ma, X, Akiyama, Y, Chen, Y, Fang, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929886/
https://www.ncbi.nlm.nih.gov/pubmed/24473398
http://dx.doi.org/10.1038/bjc.2013.808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929886/
https://www.ncbi.nlm.nih.gov/pubmed/24473398
http://dx.doi.org/10.1038/bjc.2013.808

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