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Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancer

BACKGROUND: Jumonji domain-containing protein 2B (JMJD2B), directly targeted by hypoxia-inducible factor 1α, maintains the histone methylation balance important for the transcriptional activation of many oncogenes. Jumonji domain-containing protein 2B has been implicated in colorectal cancer (CRC) p...

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Detalles Bibliográficos
Autores principales:	Chen, L, Fu, L, Kong, X, Xu, J, Wang, Z, Ma, X, Akiyama, Y, Chen, Y, Fang, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929886/ https://www.ncbi.nlm.nih.gov/pubmed/24473398 http://dx.doi.org/10.1038/bjc.2013.808

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