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Increased expression of RRM2 by human papillomavirus E7 oncoprotein promotes angiogenesis in cervical cancer

BACKGROUND: The purpose of this study was to confirm that RRM2 as a novel target of HPVE7 involved in cervical cancer angiogenesis. METHODS: Gene expression was analysed by RT-qPCR, western blot and immunohistochemistry in cervical cancer tissue and cell lines. Luciferase reporter assay was used to...

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Detalles Bibliográficos
Autores principales: Wang, N, Zhan, T, Ke, T, Huang, X, Ke, D, Wang, Q, Li, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929894/
https://www.ncbi.nlm.nih.gov/pubmed/24423925
http://dx.doi.org/10.1038/bjc.2013.817