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SIRT1 metabolic actions: Integrating recent advances from mouse models()

SIRT1 has attracted a lot of interest since it was discovered as a mammalian homolog of Sir2, a protein that influences longevity in yeast. Intensive early research suggested a key role of SIRT1 in mammalian development, metabolic flexibility and oxidative metabolism. However, it is the growing body...

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Detalles Bibliográficos
Autores principales: Boutant, Marie, Cantó, Carles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929913/
https://www.ncbi.nlm.nih.gov/pubmed/24567900
http://dx.doi.org/10.1016/j.molmet.2013.10.006