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PTTG Acts As a STAT3 Target Gene for Colorectal Cancer Cell Growth and Motility

Pituitary tumor transforming gene (PTTG), the index mammalian securin, is abundantly expressed in several tumors and regulates tumor growth and progression. Molecular mechanisms elucidating PTTG regulation and actions remain elusive. Here, we provide evidence that PTTG acts as a STAT3 target gene. T...

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Detalles Bibliográficos
Autores principales: Zhou, Cuiqi, Tong, Yunguang, Wawrowsky, Kolja, Melmed, Shlomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930149/
https://www.ncbi.nlm.nih.gov/pubmed/23416975
http://dx.doi.org/10.1038/onc.2013.16