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Staphylococcus aureus convert neonatal conventional CD4(+) T cells into FOXP3(+) CD25(+) CD127(low) T cells via the PD-1/PD-L1 axis

The gut microbiota provides an important stimulus for the induction of regulatory T (Treg) cells in mice, whether this applies to newborn children is unknown. In Swedish children, Staphylococcus aureus has become a common early colonizer of the gut. Here, we sought to study the effects of bacterial...

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Detalles Bibliográficos
Autores principales: Rabe, Hardis, Nordström, Inger, Andersson, Kerstin, Lundell, Anna-Carin, Rudin, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930383/
https://www.ncbi.nlm.nih.gov/pubmed/24708420
http://dx.doi.org/10.1111/imm.12209