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Inhibition of MAPK-mediated ACE expression by compound C66 prevents STZ-induced diabetic nephropathy
A range of in vitro, experimental and clinical intervention studies have implicated an important role for hyperglycaemia-induced activation of the renin-angiotensin system (RAS) in the development and progression of diabetic nephropathy (DN). Blockade of RAS by angiotensin converting enzyme (ACE) in...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930410/ https://www.ncbi.nlm.nih.gov/pubmed/24330074 http://dx.doi.org/10.1111/jcmm.12175 |