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α(1) adrenoceptor activation by norepinephrine inhibits LPS-induced cardiomyocyte TNF-α production via modulating ERK1/2 and NF-κB pathway

Cardiomyocyte tumour necrosis factor α (TNF-α) production contributes to myocardial depression during sepsis. This study was designed to observe the effect of norepinephrine (NE) on lipopolysaccharide (LPS)-induced cardiomyocyte TNF-α expression and to further investigate the underlying mechanisms i...

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Detalles Bibliográficos
Autores principales: Yu, Xiaohui, Jia, Baoyin, Wang, Faqiang, Lv, Xiuxiu, Peng, Xuemei, Wang, Yiyang, Li, Hongmei, Wang, Yanping, Lu, Daxiang, Wang, Huadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930413/
https://www.ncbi.nlm.nih.gov/pubmed/24304472
http://dx.doi.org/10.1111/jcmm.12184