Berberine ameliorates cartilage degeneration in interleukin-1β-stimulated rat chondrocytes and in a rat model of osteoarthritis via Akt signalling

Berberine, a plant alkaloid used in Chinese medicine, has broad cell-protective functions in a variety of cell lines. Chondrocyte apoptosis contributes to the pathogenesis of cartilage degeneration in osteoarthritis (OA). However, little is known about the effect and underlying mechanism of berberin...

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Detalles Bibliográficos
Autores principales: Zhao, Honghai, Zhang, Tongen, Xia, Chun, Shi, Lei, Wang, Shaojie, Zheng, Xinpeng, Hu, Tianhui, Zhang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930415/
https://www.ncbi.nlm.nih.gov/pubmed/24286347
http://dx.doi.org/10.1111/jcmm.12186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930415/
https://www.ncbi.nlm.nih.gov/pubmed/24286347
http://dx.doi.org/10.1111/jcmm.12186

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