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Does the cis/trans configuration of peptide bonds in bioactive tripeptides play a role in ACE-1 enzyme inhibition?
BACKGROUND: The milk casein-derived bioactive tripeptides isoleucine-proline-proline (IPP) and valine-proline-proline (VPP) have been shown to prevent development of hypertension in animal models and to lower blood pressure in moderately hypertensive subjects in most but not all clinical trials. Inh...
Autores principales: | Siltari, Aino, Viitanen, Riikka, Kukkurainen, Sampo, Vapaatalo, Heikki, Valjakka, Jarkko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930482/ https://www.ncbi.nlm.nih.gov/pubmed/24596454 http://dx.doi.org/10.2147/BTT.S54056 |
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