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k-OptForce: Integrating Kinetics with Flux Balance Analysis for Strain Design

Computational strain design protocols aim at the system-wide identification of intervention strategies for the enhanced production of biochemicals in microorganisms. Existing approaches relying solely on stoichiometry and rudimentary constraint-based regulation overlook the effects of metabolite con...

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Detalles Bibliográficos
Autores principales:	Chowdhury, Anupam, Zomorrodi, Ali R., Maranas, Costas D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930495/ https://www.ncbi.nlm.nih.gov/pubmed/24586136 http://dx.doi.org/10.1371/journal.pcbi.1003487

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