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Distinct Requirements for Cranial Ectoderm and Mesenchyme-Derived Wnts in Specification and Differentiation of Osteoblast and Dermal Progenitors

The cranial bones and dermis differentiate from mesenchyme beneath the surface ectoderm. Fate selection in cranial mesenchyme requires the canonical Wnt effector molecule β-catenin, but the relative contribution of Wnt ligand sources in this process remains unknown. Here we show Wnt ligands are expr...

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Detalles Bibliográficos
Autores principales: Goodnough, L. Henry, DiNuoscio, Gregg J., Ferguson, James W., Williams, Trevor, Lang, Richard A., Atit, Radhika P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930509/
https://www.ncbi.nlm.nih.gov/pubmed/24586192
http://dx.doi.org/10.1371/journal.pgen.1004152