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Genome-Wide Association Study of Metabolic Traits Reveals Novel Gene-Metabolite-Disease Links

Metabolic traits are molecular phenotypes that can drive clinical phenotypes and may predict disease progression. Here, we report results from a metabolome- and genome-wide association study on (1)H-NMR urine metabolic profiles. The study was conducted within an untargeted approach, employing a nove...

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Detalles Bibliográficos
Autores principales: Rueedi, Rico, Ledda, Mirko, Nicholls, Andrew W., Salek, Reza M., Marques-Vidal, Pedro, Morya, Edgard, Sameshima, Koichi, Montoliu, Ivan, Da Silva, Laeticia, Collino, Sebastiano, Martin, François-Pierre, Rezzi, Serge, Steinbeck, Christoph, Waterworth, Dawn M., Waeber, Gérard, Vollenweider, Peter, Beckmann, Jacques S., Le Coutre, Johannes, Mooser, Vincent, Bergmann, Sven, Genick, Ulrich K., Kutalik, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930510/
https://www.ncbi.nlm.nih.gov/pubmed/24586186
http://dx.doi.org/10.1371/journal.pgen.1004132