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Genome-Wide Association Study of Metabolic Traits Reveals Novel Gene-Metabolite-Disease Links
Metabolic traits are molecular phenotypes that can drive clinical phenotypes and may predict disease progression. Here, we report results from a metabolome- and genome-wide association study on (1)H-NMR urine metabolic profiles. The study was conducted within an untargeted approach, employing a nove...
Autores principales: | Rueedi, Rico, Ledda, Mirko, Nicholls, Andrew W., Salek, Reza M., Marques-Vidal, Pedro, Morya, Edgard, Sameshima, Koichi, Montoliu, Ivan, Da Silva, Laeticia, Collino, Sebastiano, Martin, François-Pierre, Rezzi, Serge, Steinbeck, Christoph, Waterworth, Dawn M., Waeber, Gérard, Vollenweider, Peter, Beckmann, Jacques S., Le Coutre, Johannes, Mooser, Vincent, Bergmann, Sven, Genick, Ulrich K., Kutalik, Zoltán |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930510/ https://www.ncbi.nlm.nih.gov/pubmed/24586186 http://dx.doi.org/10.1371/journal.pgen.1004132 |
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