Efficient Translation of Dnmt1 Requires Cytoplasmic Polyadenylation and Musashi Binding Elements

Regulation of DNMT1 is critical for epigenetic control of many genes and for genome stability. Using phylogenetic analysis we characterized a block of 27 nucleotides in the 3′UTR of Dnmt1 mRNA identical between humans and Xenopus and investigated the role of the individual elements contained within...

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Detalles Bibliográficos
Autores principales: Rutledge, Charlotte E., Lau, Ho-Tak, Mangan, Hazel, Hardy, Linda L., Sunnotel, Olaf, Guo, Fan, MacNicol, Angus M., Walsh, Colum P., Lees-Murdock, Diane J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930535/
https://www.ncbi.nlm.nih.gov/pubmed/24586322
http://dx.doi.org/10.1371/journal.pone.0088385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930535/
https://www.ncbi.nlm.nih.gov/pubmed/24586322
http://dx.doi.org/10.1371/journal.pone.0088385

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