Inactivation of the Host Lipin Gene Accelerates RNA Virus Replication through Viral Exploitation of the Expanded Endoplasmic Reticulum Membrane

RNA viruses take advantage of cellular resources, such as membranes and lipids, to assemble viral replicase complexes (VRCs) that drive viral replication. The host lipins (phosphatidate phosphatases) are particularly interesting because these proteins play key roles in cellular decisions about membr...

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Detalles Bibliográficos
Autores principales: Chuang, Chingkai, Barajas, Daniel, Qin, Jun, Nagy, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930575/
https://www.ncbi.nlm.nih.gov/pubmed/24586157
http://dx.doi.org/10.1371/journal.ppat.1003944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930575/
https://www.ncbi.nlm.nih.gov/pubmed/24586157
http://dx.doi.org/10.1371/journal.ppat.1003944

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