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The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling

Chlamydia trachomatis, the causative agent of trachoma and sexually transmitted infections, employs a type III secretion (T3S) system to deliver effector proteins into host epithelial cells to establish a replicative vacuole. Aside from the phosphoprotein TARP, a Chlamydia effector that promotes act...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Shan, Bastidas, Robert J., Saka, Hector A., Carpenter, Victoria K., Richards, Kristian L., Plano, Gregory V., Valdivia, Raphael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930595/
https://www.ncbi.nlm.nih.gov/pubmed/24586162
http://dx.doi.org/10.1371/journal.ppat.1003954