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The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling
Chlamydia trachomatis, the causative agent of trachoma and sexually transmitted infections, employs a type III secretion (T3S) system to deliver effector proteins into host epithelial cells to establish a replicative vacuole. Aside from the phosphoprotein TARP, a Chlamydia effector that promotes act...
Autores principales: | Chen, Yi-Shan, Bastidas, Robert J., Saka, Hector A., Carpenter, Victoria K., Richards, Kristian L., Plano, Gregory V., Valdivia, Raphael H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930595/ https://www.ncbi.nlm.nih.gov/pubmed/24586162 http://dx.doi.org/10.1371/journal.ppat.1003954 |
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