Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain

JC virus is a member of the Polyomavirus family of DNA tumor viruses and the causative agent of progressive multifocal leukoencephalopathy (PML). PML is a disease that occurs primarily in people who are immunocompromised and is usually fatal. As with other Polyomavirus family members, the replicatio...

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Detalles Bibliográficos
Autores principales: Meinke, Gretchen, Phelan, Paul J., Kalekar, Radha, Shin, Jong, Archambault, Jacques, Bohm, Andrew, Bullock, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930596/
https://www.ncbi.nlm.nih.gov/pubmed/24586168
http://dx.doi.org/10.1371/journal.ppat.1003966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930596/
https://www.ncbi.nlm.nih.gov/pubmed/24586168
http://dx.doi.org/10.1371/journal.ppat.1003966

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