Engineering a single ubiquitin ligase for the selective degradation of all activated ErbB receptor tyrosine kinases

Interrogating specific cellular activities often entails the dissection of posttranslational modifications or functional redundancy conferred by protein families, which demands more sophisticated research tools than simply eliminating a specific gene product by gene targeting or RNAi. We have develo...

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Detalles Bibliográficos
Autores principales: Kong, Fanming, Zhang, Jianxuan, Li, Yuewei, Hao, Xishan, Ren, Xiubao, Li, Hui, Zhou, Pengbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930622/
https://www.ncbi.nlm.nih.gov/pubmed/23416973
http://dx.doi.org/10.1038/onc.2013.33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930622/
https://www.ncbi.nlm.nih.gov/pubmed/23416973
http://dx.doi.org/10.1038/onc.2013.33

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