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Engineering a single ubiquitin ligase for the selective degradation of all activated ErbB receptor tyrosine kinases
Interrogating specific cellular activities often entails the dissection of posttranslational modifications or functional redundancy conferred by protein families, which demands more sophisticated research tools than simply eliminating a specific gene product by gene targeting or RNAi. We have develo...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930622/ https://www.ncbi.nlm.nih.gov/pubmed/23416973 http://dx.doi.org/10.1038/onc.2013.33 |