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Acute Lymphoid Leukemia Cells with Greater Stem Cell Antigen-1 (Ly6a/Sca-1) Expression Exhibit Higher Levels of Metalloproteinase Activity and Are More Aggressive In Vivo

Stem cell antigen-1 (Ly6a/Sca-1) is a gene that is expressed in activated lymphocytes, hematopoietic stem cells and stem cells of a variety of tissues in mice. Despite decades of study its functions remain poorly defined. These studies explored the impact of expression of this stem cell associated g...

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Detalles Bibliográficos
Autores principales: Hsu, Yu-Chiao, Mildenstein, Kurt, Hunter, Kordell, Tkachenko, Olena, Mullen, Craig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930640/
https://www.ncbi.nlm.nih.gov/pubmed/24586463
http://dx.doi.org/10.1371/journal.pone.0088966